WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

This table lists the enriched KEGG pathways, number of Entrez IDs in your user data set for the pathway, the corresponding Entrez IDs, and the statistics for the enriched pathway.
The statistic column lists:
Finally, the pathway name is linked to KEGG where the user ids are highlighted, the number of user gene ids is linked to a table with information about the user ids, and the Entrez IDs are linked to Entrez Gene.

PathwayName #Gene EntrezGene Statistics
Shigellosis 18 391 8767 71 5879 3678 10093 10459 10094 25 10095 998 10092 9844 5216 4790 60 10109 5970 C=61;O=18;E=1.22;R=14.80;rawP=1.23e-16;adjP=1.91e-14
Bacterial invasion of epithelial cells 18 391 387 71 5295 5879 3678 10093 10459 10094 6464 10095 998 10092 9844 1211 60 10109 79658 C=70;O=18;E=1.40;R=12.90;rawP=1.83e-15;adjP=1.42e-13
Metabolic pathways 64 80025 9942 1355 8760 2026 9060 4594 7357 7358 26229 8877 427 445 353 9388 22856 2639 5373 8659 27430 8818 533 1890 3631 220 622 4831 3155 30833 10558 2023 4129 79888 51703 5625 2651 4860 29968 1371 84618 157506 53354 1353 205 79623 5831 5320 51109 159 1594 29880 36 10993 5859 5634 8560 47 38 3614 5437 85365 9533 65220 3712 C=1130;O=64;E=22.53;R=2.84;rawP=1.20e-13;adjP=6.20e-12
Pathogenic Escherichia coli infection 15 25 387 7280 998 10095 71 10092 347733 7534 60 10093 10109 203068 10094 10376 C=56;O=15;E=1.12;R=13.43;rawP=2.11e-13;adjP=8.18e-12
Neurotrophin signaling pathway 20 387 8767 4794 5295 5879 7157 5908 4804 25 6464 3654 998 5580 4790 3656 396 581 7534 5970 7533 C=127;O=20;E=2.53;R=7.90;rawP=1.08e-12;adjP=3.35e-11
Cytokine-cytokine receptor interaction 25 7040 6354 3455 3460 3601 6364 1236 84957 23529 8795 3597 4804 3563 80301 3554 4055 5154 1435 7132 23765 9180 3082 3566 8740 8792 C=265;O=25;E=5.28;R=4.73;rawP=1.86e-10;adjP=4.27e-09
Apoptosis 15 3554 3654 8795 3656 4790 5295 7157 7132 581 5534 8737 4615 5970 3563 8837 C=87;O=15;E=1.73;R=8.65;rawP=1.93e-10;adjP=4.27e-09
Fc gamma R-mediated phagocytosis 15 7408 998 10095 2209 10092 5580 5295 5879 8877 65108 10093 382 10109 1072 10094 C=94;O=15;E=1.87;R=8.00;rawP=5.99e-10;adjP=1.16e-08
Focal adhesion 21 387 71 7058 5295 5879 5908 3678 3371 1293 7057 5154 7791 7408 3675 6464 998 3479 60 3082 83660 1288 C=200;O=21;E=3.99;R=5.27;rawP=7.51e-10;adjP=1.29e-08
Purine metabolism 18 9060 4860 84618 5137 2766 205 353 2984 159 111 5634 4831 109 124583 3614 30833 5437 9533 C=162;O=18;E=3.23;R=5.57;rawP=4.94e-09;adjP=7.66e-08


WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).